Naomie Harris as Dr. Kate Caldwell; Marley Shelton as Dr. Kerry Atkins; Jeffrey Dean Morgan as Agent Harvey Russell; Malin Akerman as Claire Wyden; Dwayne Johnson as Davis Okoya; Joe Manganiello as Burke; Jake Lacy as Brett Wynden
Primatologist Davis Okoye shares an unshakable bond with George, the extraordinarily intelligent, silverback gorilla who has been in his care since birth. But a rogue genetic experiment gone awry mutates this gentle ape into a raging creature of enormous size. To make matters worse, itï¿½s soon discovered there are other similarly altered animals. As these newly created alpha predators tear across North America, destroying everything in their path, Okoye teams with a discredited genetic engineer to secure an antidote, fighting his way through an ever-changing battlefield, not only to halt a global catastrophe but to save the fearsome creature that was once his friend.